The basis of PK/PD approach for antibiotics (Toulouse, 2023)
Lectures
- Introduction of PK/PD approach for antimicrobial drugs
- PD assessment for antimicrobial drugs
- PK/PD efficacy indices for antibiotics
- PK/PD and antimicrobial resistance
- Clinical breakpoints for AST and PK/PD
Exercise on PD data (Time-kill cruves)
- Exercise 1 – analysis of Time-kill curves
- Exercise 1 – additional file (sigmoid fitting)
- Exercise 1-correction
Exercise on PK/PD from “clinical” cases
- Exercise 2- Cases
- Excercise 2- Cases with collected data
Courses on PK/PD (Thessaloniki, 2022)
Lectures
- Introduction of PK/PD approach for antimicrobial drugs
- PD assessment for antimicrobial drugs
- PK/PD efficacy indices for antibiotics
- PK/PD and antimicrobial resistance
- Clinical breakpoints for AST and PK/PD
Exercise on PD data (Time-kill cruves)
- Exercise 1 – analysis of Time-kill curves
- Exercise 1 – additional file (sigmoid fitting)
- Exercise 1-correction
Exercise on PK/PD from “clinical” cases
INTRODUCTION TO PHARMACOKINETICS
Short introductive videos provided by Prof. Ronette Gehring
https://www.youtube.com/channel/UCqIzR7scMVM96_cfNUuPRow
Reviews on the main pharmacokinetic parameters
Courses on Pharmacokinetics (Padua, 2021)
- 1 Pharmacokinetics and pharmacodynamics – An overview
- 2 Drug elimination – Clearance
- 3-4 Bioavailability and plasma protein binding
- 5 Distribution
- 6 Exercise 1
- 6 Multiple Dosing Simulations
- 6 Exercise 1 Correction
- 7 Renal clearance
- 8 Hepatic clearance
- 9 Exercise 2
- 9 Exercise 2 Correction